Generic Cialis is one of the best-selling and most efficient medical drugs ordered for the treatment of male erectile dysfunction (ED) of various origin. Its active drug substance – tadalafil – is also found in some other branded medicines such as Adcirca, which is prescribed for treating pulmonary arterial hypertension and prostatic hyperplasia (prostate enlargement) of benign nature.
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Ever since Cialis (tadalafil) received approval from the U.S. Food and Drug Administration for mass distribution and use in December 2003, the drug has been widely recognized as one of the most robust and low-risk medications prescribed to male patients who struggle to get an erection and keep it firm throughout the entire sexual intercourse. Any man taking Cialis needs to remember that the drug is only going to be effective if there is sexual arousal present.
How Does Generic Cialis Affect Men’s Sexual Potency to Cause Prolonged Erection?
The drug’s mechanism of action is in many ways similar to that of Viagra (sildenafil) and Levitra (vardenafil). All of these medications belong to the group of selective phosphodiesterase 5 (PDE5) inhibitors that work towards suppressing the output of PDE5, which is an enzyme chiefly responsible for stopping an erection. Its selectiveness stems from the fact that Cialis specifically targets and inhibits the PDE5-type enzyme while having little or no negative impact on other types of PDEs like PDE3 that participates in the cardiac muscle contractions or PDE6, which is responsible for proper work of photoreceptors.
Administered orally, a Cialis pill usually begins functioning in about 30 minutes. The drug maximizes blood flow to the penis by relaxing its smooth muscle tissue and dilating the vessels therein. This causes blood to rush to the penis and stay there for some time. That is how an erection occurs. Once the man has had an orgasm, normal blood circulation is restored, and the penis becomes flaccid again. However, with Cialis still in the system, sexual intercourse can continue for up to 36 hours.
So Why Does ED Make Men’s Blood Run Cold?
Over 152 million men around the world are known to suffer from erectile dysfunction. The statistics available on the subject indicate that more than 50 percent of men over the age of 40 are at risk of developing ED.
Sexual disorders, such as decreased sexual interest, easy disruption of sexual arousal, inability to get and maintain a firm erection, erectile dissatisfaction, are some of the most traumatic psychologic experiences in any man’s life. Modern medicine considers sexual virility to be a necessary condition for men’s physical well-being and their mental health.
However, erectile disorders are not necessarily a reason to get concerned; that might just be how your body tells you something is not working the way it should, and you need to see a doctor. There are many different physical and psychological issues that can cause erectile dysfunction in men. With the elimination of these, you can get back to your normal sex life.
Erectile dysfunction can often be a symptom of the following physical health problems:
- cardiovascular diseases
- diabetes
- obesity
- testosterone deficiency
- spinal cord or pelvic injuries
- elevated levels of cholesterol
- multiple sclerosis
- enlargement of prostate
- insulin resistance syndrome
- smoking or substance abuse
- physical fatigue
Among the most common psychological causes of ED, there are:
- mental conditions
- chronic stress
- anxiety
- depression
- sense of guilt or low self-esteem
Sometimes, erectile dysfunction can be the result of a combination of physical and psychological factors, which means a more complex approach to its treatment is required.
What ED Treatment Options Can Men Choose From?
Today, there are plenty of ways to deal with erectile dysfunction. For example, some men who struggle to get a satisfactory erection or stay erect for a long enough time opt for injections administered directly into the penis shortly before the intended sexual intercourse to stimulate better penile blood flow. Although this method has proven to be quite safe and effective, with time, a lot of men using it develop a neurotic fear of sex that they subconsciously associate with pain sensations caused by penile injections.
Other men go for a less radical method and choose a vacuum constriction device. When pumped by hand or automatically, the VCD draws blood to the penis shaft, making it swollen and erect.
Finally, if none of these methods works, the only option left is surgical treatment. Such surgery involves the insertion of a special penile prosthesis (implant). With this implant placed directly into the penis and connected to a pump inside the scrotum, men can engage in sex more spontaneously.
Compared to the said methods, taking a single oral pill 30 minutes before the planned sex and then enjoying up to 36 hours of firm uninterrupted erection sounds downright fantastic.
What Makes Generic Cialis A Better Alternative to Other PDE5 Inhibitor Pills Used to Treat ED?
Although the serendipitous discovery of Viagra (sildenafil) has revolutionized how erectile dysfunction in men is treated today, it is now evident that the ‘magic blue pill’ is not that magic after all. To start with, it is not equally effective and suitable for everyone, with many alarming adverse reactions like migraines, digestive disturbance, and severe muscle pains frequently reported. Viagra’s duration of action is limited to only 4-6 hours, which makes it harder to pre-plan sexual intercourse. Furthermore, such factors as alcohol consumption or eating fatty foods can interact with the absorption of the drug and lead to its decreased effectiveness.
When scientists realized that Viagra was not the end-all answer to the problem of treating male erectile dysfunction, they decided to modify its molecular formula to try to obtain a new, improved ED treatment solution. The result of such experiments was the development of tadalafil (distributed under the brand name of Cialis), which is a more potent ED medication, with a much better safety and efficacy record. The new drug is absorbed into the bloodstream quicker, and its effect is not lessened by the intake of food or alcohol.
Among other distinct advantages that separate Cialis from older PDE5 inhibitor meds, which are usually prescribed for the ED treatment, there are:
- quick onset (Cialis starts to have effect in just about 20-30 minutes upon its administration)
- much longer duration of action (up to 36 hours, which allows for multiple intercourse attempts)
- much more flexible dosing (a single dose of the drug can vary from 2.5 mg to 20 mg depending on the desired outcome)
- lower risk of developing resistance to the medication (that is why Cialis is often prescribed for the long-term ED treatment in the form of 2.5 mg once-daily dose of tadalafil)
- the prolonged half-life of up to 18 hours (which means it is easier for patients taking Cialis to separate drug administration from sexual intercourse and re-introduce more spontaneity into their sex life)
When Is It Not Safe to Start or Continue Taking Generic Cialis?
Like any other synthetic substance, Cialis is not entirely risk-free. This medication has quite a few side effects as well as a range of contraindications that make it unsuitable for certain groups of patients.
Thus, Cialis is contraindicated if the patient has one of the following health problems:
- heart conditions or pains in the chest that are being medicated with organic nitrate drugs (co-administration with Cialis can lead to a sudden and dangerous drop of blood pressure)
- an apoplectic stroke or a congestive cardiac failure suffered in the past 6 months
- a cardiovascular accident suffered in the past 3 months
- severe blood diseases like hematophilia, leukocytic sarcoma, microdrepanocytic anemia
- hepatic or renal disorders
- peptic ulcer
- tapetoretinal degeneration
- penile fibromatosis
It is also best to avoid co-administering Cialis with some antifungal medications (ketoconazole), antiretroviral drugs (ritonavir), PAH meds (riociguat), alpha-blockers (tamsulosin, doxazosin), macrolide antibiotic drugs (roxithromycin, erythromycin, azithromycin), HCV protease inhibitors (telaprevir, boceprevir), antiepileptic drugs (phenytoin, carbamazepine, primidone, oxcarbazepine, phenobarbital). When taken alongside Cialis, some of these medicinal products can change the way tadalafil works, or be changed by it. Consult your doctor before you start or stop taking any drugs, or alter their dosage.
The most commonly observed side effects of Cialis include headaches, indigestion, nasal blockage, and heat waves. Although they may cause certain discomfort, these symptoms are generally not considered dangerous and usually disappear quickly. However, if they linger about or get worse, patients are advised to call their doctor for advice.
Cialis can rarely cause the following, more disturbing, adverse reactions: impaired vision, hearing difficulty, extreme dizziness, protracted and painful erection. Also, you may happen to be allergic to the drug’s main active ingredient – tadalafil – in which case, there will be signs of an allergic reaction, like an itchy rash, labored breathing, rapid swelling of the tongue, throat, or face. All of these symptoms are highly serious and should never be overlooked. If you start experiencing any of them after taking a pill of Cialis, get urgent medical aid.
How to Take Generic Cialis to Achieve Greater Effectiveness?
The suitable dosage of Cialis for treating ED is determined by your doctor, who is familiar with your medical history, knows about any past or present conditions in which Cialis is contraindicated, and has any other information that might be useful in this situation. The average dose of the drug is 10 mg, taken 30 minutes before the planned coitus. However, based on the severity of your problem, the anticipated outcome, and your overall response to the treatment, the tablet strength can be lowered to 2.5-5 mg or raised to up to 20 mg.
Original Cialis vs Its Generic Versions: Is There Any Difference?
Original Cialis, developed by the French drug manufacturer Eli Lilly, first went on sale in December 2003, and the company enjoyed a long period of exclusivity with its medication before generic versions were officially allowed. Today, Cialis is slowly losing its leadership position in the European market, making room for high quality and less expensive generic analogs. There is a wide range of generic Cialis products available on drugstore shelves and online that vary in strength and application frequency. Some lower-dose generic Cialis meds are to be taken just once every day, while others, with a higher dosage, can be used on an as-needed basis, not long before the anticipated coitus.
The main selling point for Cialis generic drugs is a much more affordable price; however, many people are concerned about their safety. The record shows that most of these medications are equal in quality and efficacy to the original drug, and their reduced cost results from the fact that their manufacturers do not need to spend money on the R&D, design, and marketing activities. That said, there are quite a few dishonest manufacturers out there who deceive their customers by changing the proportion of the ingredients of the medicine or substituting those with cheaper and often less effective components. That is why it is crucial for customers to always stay alert and avoid purchasing meds like generic Cialis from doubtful sources.
The Bottom Line
The bitter truth is, one out of three men faces erectile dysfunction problems at some point throughout their life. Even though this is an extremely distressing experience, only 40 percent of those afflicted by it are likely to see a doctor and get proper treatment. In the 21st century, there is still too much misleading information and stereotypes surrounding the topic that make it even more difficult for men to be open about their ED problems.
Fortunately, there are many safe and budget-friendly solutions for treating male erectile dysfunction, Cialis being one of them. It is a mighty and reliable ED medication with fewer side effects and prolonged action, which allows men to regain their self-confidence and make their sexual relationship more spontaneous and, therefore, more enjoyable.
Important Disclaimer:
This page contains information related to drugs, their pharmacokinetic and pharmacodynamic characteristics, safety of their use, administration instructions, available doses, conditions they are used to address, generic posological schedules and other such materials. This information reflects the general guidelines available in a variety of sources like manufacturer’s insert to medical products and are mentioned with educational purposes only. Users should approach these materials with full understanding that they are not intended as direct instructions to follow without doctor’s approval. Professional oppinion and instructions should be obtained and followed at any time. Names of brands, companies and products belong to their copyright owners.
